Polynucleotides (Skin Bio-revitalisation)

Understanding Polynucleotides:
Polynucleotides (PN) have emerged as a highly effective supportive therapy for wound and skin healing. Extensively researched for over four decades, they have been used in regenerative medicine for 35 years. Dr. Anita Dhunna exclusively offers the most safe and effective polynucleotides products – Plenyhage® XL medium and Plenyhage® XL Strong, Newest and PLINEST – developed in prestigious Italian laboratories. These polynucleotides are biomolecules composed of long-chain nucleotides, the building blocks of DNA and RNA. Ethically sourced from salmon and trout sperm, these molecules are sterilised and purified before being skilfully injected into the layers of the dermis, precisely targeting various areas of the face and body.

Polynucleotides play a pivotal role in stimulating fibroblast activity, thus accelerating collagen production and the growth of fibroblasts. By activating and rejuvenating damaged or aging skin cells, they foster the production of new matrix glycosaminoglycans, collagen, and elastin fibres. Notably, the regeneration of fibroblasts has been clinically proven to significantly enhance skin quality and texture in the mid-layers of the skin, yielding lasting improvements.

The presence of Protamine Sulphate in salmon and trout sperm, rich in arginine content, contributes to the highly restorative effects on the skin. The result is a smoother, more resilient complexion with a rejuvenated, dewy glow owing to renewed hydration.

Mechanisms of Polynucleotide Action:
Administered by a qualified medical professional like Dr. Anita Dhunna, polynucleotides exhibit the ability to attract and retain water molecules within the skin. This comprehensive hydration restores aging and damaged skin, while also offering an anti-free radical action by neutralising harmful OH hydroxyl radicals. These radicals often accumulate due to various internal and external factors like stress, UV radiation, and environmental pollution. Furthermore, polynucleotides activate the body’s natural fibroblast production, promoting new cellular growth and activity causing significant regeneration of the skin

Versatility in Treatment:
Polynucleotides offer a versatile range of treatments, including addressing the initial signs of aging, acne atrophic scars, hair loss, trauma or surgical scars, UV damage, hyperpigmentation, rosacea, stretch marks, and even dark circles. They serve as excellent alternatives to tear trough fillers for individuals with hypersensitivity to hyaluronic acid (HA) products.

Treatment Areas:
The adaptability of polynucleotides extends to various treatment areas, encompassing the face, neck, scalp, décolleté, upper arms, hands, thighs, and stomach.

Differentiating from Dermal Fillers:
Unlike traditional HA dermal fillers that hydrate the skin with a gel substance, injectable polynucleotide DNA fractions operate on a cellular level. These molecules act as wound healing agents, followed by cell renewal, inflammation reduction, hydration, and skin repair. However, it’s important to note that while polynucleotides excel in these aspects, they cannot sculpt facial contours like dermal fillers. Consequently, combining polynucleotides with dermal fillers and Botox® can create a holistic anti-aging and facial re-sculpting regimen.

Minimal Side Effects, Maximum Results:
Extracted from fish, polynucleotides boast high bio-compatibility with human skin, resulting in minimal immunological side effects. While there is no clinical downtime associated with polynucleotide injections, mild tenderness, minor bumps at injection sites, and occasional bruising are normal cosmetic side effects. These can be mitigated using ice, arnica tablets, and creams. Patients with fish allergies should refrain from polynucleotide treatments.

Comfort and Suitability:
Thanks to the use of numbing cream and expertly administered injections, patients experience minimal discomfort. Before undergoing a polynucleotide treatment, a pre-treatment consultation, skin analysis, and medical history assessment with Dr. Anita Dhunna ensure both suitability and safety.

Tailored Treatment Plans:
The number of required treatments depends on individual needs and whether treatment targets the face or body. Generally, a course of three treatments, spaced 2 to 4 weeks apart, yields optimal results.

Efficient Time Investment:
A typical injectable polynucleotide treatment, including numbing cream activation, takes around 45 to 60 minutes, ensuring efficient yet comprehensive care.

Longevity of Results:
The cumulative results of a polynucleotide treatment can last up to 12 months. To maintain results after the initial course, single treatments every 6 to 9 months are recommended.